{"id":6419,"date":"2024-01-25T13:10:38","date_gmt":"2024-01-25T11:10:38","guid":{"rendered":"https:\/\/kwadronpmu.com\/makijaz-permanentny-ze-znieczuleniem-czy-bez\/"},"modified":"2025-01-13T15:52:34","modified_gmt":"2025-01-13T13:52:34","slug":"permanent-makeup-with-or-without-anesthesia","status":"publish","type":"post","link":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia","title":{"rendered":"Permanent Makeup: With or Without Anesthesia?"},"content":{"rendered":"<div id=\"pl-6419\"  class=\"panel-layout\" ><div id=\"pg-6419-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-0-0-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png 1080w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-300x300.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1024x1024.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-150x150.png 150w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-768x768.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-400x400.png 400w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-420x420.png 420w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-200x200.png 200w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-600x600.png 600w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-100x100.png 100w\" sizes=\"(max-width: 300px) 100vw, 300px\" title=\"lips-pmu098\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><\/div><div id=\"pgc-6419-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"1\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>&nbsp;<\/p>\n<h3>Permanent Makeup: With or Without Anesthesia?<\/h3>\n<h5>MARTA KOT-PAKULSKA<\/h5>\n<p><em>Article published in <a href=\"http:\/\/Article published in Kosmetologia Estetyczna magazine (in Polish). MARTA KOT-PAKULSKA\">Kosmetologia Estetyczna<\/a> magazine (2023\/3).<\/em><\/p>\n<\/p>\n<p>&nbsp;<\/p>\n<p>Permanent Makeup, also known as micropigmentation or lasting makeup, has become incredibly popular among those looking to save time and effort on their daily beauty routine. One of the common questions asked by individuals opting for permanent makeup is about the pain involved. Is anesthesia necessary? Can micropigmentation be done without pain relief?<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-0-1-1\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"2\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-f54c0409268f-6419\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\">\n\t<a\n\thref=\"https:\/\/kwadronpmu.com\/en\/products\/\"\n\t\tclass=\"ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\" \t>\n\t\t<span>\n\t\t\t\n\t\t\tGet to know our PMU products\t\t<\/span>\n\t<\/a>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-1-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-1-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-1-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"3\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Responses to pain are highly individual. What may be a gentle discomfort for some could be quite painful for others. Therefore, the decision to use anesthesia for permanent makeup procedures depends on the client's preferences and needs, as well as the recommendations and qualifications of the specialist. In the case of anesthesia administered by micropigmentation professionals, decisions and procedures related to anesthesia are regulated by the laws and health regulations in the respective country. The practitioner must adhere to these regulations, obtain the necessary qualifications, and be licensed to administer anesthesia.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-2\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-2-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-2-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-2-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"4\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>&nbsp;<\/p>\n<h3>PAIN<\/h3>\n<p>During the process of permanent makeup application, the continuity of the skin is disrupted, which is rich in receptors that receive stimuli from the environment and transmit information to the brain. Pain is defined as an unpleasant sensory and emotional experience accompanying actual or potential tissue damage. The purpose of anesthesia is to eliminate this experience.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-3\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-3-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-3-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-3-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"5\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>TOPICAL ANESTHESIA<\/h3>\n<p>Topical anesthesia is achieved using prilocaine, benzocaine, and lidocaine. Preparations available on the market are often a mixture of two or more of these agents. They do not contain vasoconstrictors, as the addition of such substances would hinder the absorption of the pain-relieving components.<\/p>\n<h5>Benzocaine<\/h5>\n<p>It is an ester of p-aminobenzoic acid (PABA) and ethanol (ethyl alcohol, C2H5OH). It is known for its rapid action, typically taking effect within 15-30 seconds. The duration of its action is approximately 12-15 minutes. It stabilizes the membrane of nerve cells by inhibiting the flow of ions necessary for the generation and conduction of impulses.<\/p>\n<h5>Lidocaine<\/h5>\n<p>Lidocaine is an amid-type agent with a benzene ring, metabolized in the liver. It is used for both local and topical anesthesia, recognized as one of the safest anesthetic agents suitable for individuals of all ages. In local anesthesia preparations, it is commonly used as a 2% solution of lidocaine hydrochloride, with or without the addition of adrenaline at concentrations of 1:50,000, 1:80,000, and 1:100,000. Known for its fast onset, lidocaine stabilizes the membranes of nerve cells by inhibiting the flow of sodium ions, crucial for the generation and conduction of nerve impulses. The duration of lidocaine's effect depends on the administration site, dosage, and the addition of vasoconstrictor medications.<\/p>\n<h5>Prilocaine<\/h5>\n<p>It stabilizes the membranes of nerve cells, inhibiting the generation and conduction of nerve impulses. Compared to lidocaine, it has equivalent strength but offers a longer duration of action, lower toxicity, and undergoes hepatic metabolism more rapidly<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-4\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-4-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-4-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-4-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"6\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>Surface Anesthetics Applied to Uninterrupted Skin Areas<\/h3>\n<p>These surface anesthetics, often referred to as primary in the beauty industry, typically come in the form of a cream applied to cleansed and disinfected skin. This method allows for the numbing of any pigmented part of the body, such as eyebrows, lips, and eyelids. A common dilemma for novice practitioners is when to apply the cream \u2013 before or after the preliminary drawing. If applied before, there may be concerns about the cream's effectiveness, and if applied after, there's a worry it might negatively impact the project.<\/p>\n<p>There's no one-size-fits-all answer to this question. However, it's essential to consider that applying anesthesia after the preliminary drawing may alter the skin's structure \u2013 tissues may become swollen and softened under occlusion. There's a significant risk that, despite the numbing, the practitioner might inadvertently tattoo too deeply, leading to client discomfort. The consequences of such work can include scarring, hair loss, uneven pigment absorption, overly intense results, patches, and pigment spreading (photo 1, 2).<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-4-1-1\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"7\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-f54c0409268f-6419\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\">\n\t<a\n\thref=\"https:\/\/kwadronpmu.com\/en\/products\/\"\n\t\tclass=\"ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\" \t>\n\t\t<span>\n\t\t\t\n\t\t\tGet to know our PMU products\t\t<\/span>\n\t<\/a>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-5\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-5-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><div id=\"pg-6419-6\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-6-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-6-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-6-1-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"8\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1.png 2160w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-300x150.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-1024x512.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-768x384.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-1536x768.png 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-2048x1024.png 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2-1-600x300.png 600w\" sizes=\"(max-width: 600px) 100vw, 600px\" title=\"ke-martakotpakulska-fot1\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-6419-6-1-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"9\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em><strong>Photo 1<\/strong>: Eyebrows after an unsuccessful permanent makeup procedure using the shading method.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-6419-6-2\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-6-2-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"10\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1.png 2160w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-300x150.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-1024x512.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-768x384.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-1536x768.png 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-2048x1024.png 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/3-1-600x300.png 600w\" sizes=\"(max-width: 600px) 100vw, 600px\" title=\"ke-martakotpakulska-fot2\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-6419-6-2-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"11\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em><strong>Photo 2:<\/strong> Eyebrows after an unsuccessful permanent makeup procedure using the microblading method. Scars and spilled pigment under the skin are visible.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-7\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-7-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-7-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-7-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"12\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n<div class=\"elementor-element elementor-element-4b425c7 elementor-widget elementor-widget-text-editor\" data-id=\"4b425c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h3>LOCAL ANESTHESIA - Mechanism of Action of Lidocaine and Prilocaine<\/h3>\n<p>Local anesthetics are characterized by an amide structure. Their mechanism of action involves blocking sodium channels, leading to the inhibition of rapid sodium ion flow and preventing depolarization of the neuron in response to stimuli. In an oil-in-water emulsion preparation, both substances form a eutectic mixture (concentration 2.5%). At room temperature, they are in liquid form, enhancing the penetration of the preparation into the deeper layers of the skin and absorption into the circulation.<\/p>\n<p>After applying the preparation to intact skin, it is absorbed into the skin depths for at least an hour under an occlusive dressing, providing anesthesia to a depth of 2-3 mm, which persists for 1-2 hours after removing the dressing. Initially, there is vasoconstriction, followed by vasodilation.<\/p>\n<\/div>\n<h3><\/h3>\n<h3><\/h3>\n<h3>Other substances included in anesthetics and their effects<\/h3>\n<\/div>\n<\/div>\n<h5>Bupivacaine<\/h5>\n<p>A long-acting amid-type agent, metabolized in the liver. Its potency and duration of action are four times greater than lidocaine. The addition of adrenaline only slightly prolongs its duration.<\/p>\n<h5>Tetracaine<\/h5>\n<p>An ester of benzoic acid and a potent, long-acting local anesthetic. It stabilizes the nerve cell membrane, preventing the generation and conduction of electrical impulses. It is characterized by an extended duration of action due to a slower rate of hydrolysis by pseudocholinesterase in the plasma. Tetracaine can be combined with adrenaline.<\/p>\n<p>Local anesthetics also contain vasoconstrictors: adrenaline or noradrenaline. The addition of these substances constricts blood vessels at the application site, reduces drug absorption, lowers the risk of overdose and bleeding, and extends the duration of action.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-8\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-8-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-8-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-8-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"13\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>CONTRAINDICATIONS<\/h3>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-8-1-1\" class=\"so-panel widget widget_sow-editor\" data-index=\"14\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Contraindications for the use of vasoconstrictors:<\/p>\n<p>\u2022\u00a0Hyperthyroidism (adrenaline),<\/p>\n<p>\u2022\u00a0Taking antidepressants (noradrenaline), such as phenothiazines, MAO inhibitors,<\/p>\n<p>\u2022\u00a0Individuals who have undergone radiotherapy in the face and skull area,<\/p>\n<p>\u2022\u00a0Individuals who have had a cerebral hemorrhage,<\/p>\n<p>\u2022\u00a0Children and adults with heart rhythm disorders,<\/p>\n<p>\u2022\u00a0Children and adults with a chromaffin tumor,<\/p>\n<p>\u2022\u00a0Individuals with uncontrolled diabetes,<\/p>\n<p>\u2022\u00a0Poorly controlled hypertension,<\/p>\n<p>\u2022\u00a0Individuals allergic to sulfites \u2013 preservatives in anesthetics with adrenaline contain sulfites.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-8-1-2\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"15\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-f54c0409268f-6419\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\">\n\t<a\n\thref=\"https:\/\/kwadronpmu.com\/en\/products\/\"\n\t\tclass=\"ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\" \t>\n\t\t<span>\n\t\t\t\n\t\t\tGet to know our PMU products\t\t<\/span>\n\t<\/a>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-9\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-9-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-9-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-9-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"16\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>Aminoesters and Aminoamides<\/h3>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-10\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-10-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-10-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-10-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"17\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h5>Aminoesters<\/h5>\n<p>Undergo breakdown in the bloodstream and may cause allergic reactions.<\/p>\n<h5>Aminoamides<\/h5>\n<p>Metabolize in the liver. Rarely cause allergic reactions.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-11\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-11-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-11-1\"  class=\"panel-grid-cell panel-grid-cell-mobile-last\" ><div id=\"panel-6419-11-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"18\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em><strong>Tabela 1<\/strong>. Classification of Local Anesthetics Based on Chemical Structure.<\/em><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-11-1-1\" class=\"so-panel widget widget_sow-image\" data-index=\"19\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1.png 2160w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-300x150.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-1024x512.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-768x384.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-1536x768.png 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-2048x1024.png 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/1-1-600x300.png 600w\" sizes=\"(max-width: 600px) 100vw, 600px\" title=\"ke-martakotpakulska-tabela1\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-6419-11-1-2\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"20\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em>Source: Author's own compilation<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-6419-11-2\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><div id=\"pg-6419-12\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-12-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-12-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-12-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"21\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Both types, in addition to their local effects, can trigger systemic toxic reactions. Such situations arise as a result of anesthetic overdose, intravascular injection, or accumulation due to multiple injections.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-13\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-13-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-13-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-13-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"22\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>DISTURBING SYMPTOMS<\/h3>\n<p>&nbsp;<\/p>\n<h5>Symptoms indicating the onset of a toxic reaction:<\/h5>\n<p>\u2022 Metallic taste, disturbances in sensation on the tongue and lips,<\/p>\n<p>\u2022 Dizziness, drowsiness,<\/p>\n<p>\u2022 Slurred speech,<\/p>\n<p>\u2022 Muscle tremors,<\/p>\n<p>\u2022 Visual disturbances,<\/p>\n<p>\u2022 Restlessness.<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-13-1-1\" class=\"so-panel widget widget_sow-editor\" data-index=\"23\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h5><\/h5>\n<h5>Symptoms of severe poisoning include:<\/h5>\n<p>\u2022\u00a0 Agitation, seizures,<\/p>\n<p>\u2022\u00a0 Coma,<\/p>\n<p>\u2022\u00a0 Respiratory arrest,<\/p>\n<p>\u2022\u00a0 Cardiac rhythm disturbances, bradycardia,<\/p>\n<p>\u2022\u00a0 Heart failure and cardiac arrest.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-13-1-2\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"24\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n<div class=\"elementor-element elementor-element-4b425c7 elementor-widget elementor-widget-text-editor\" data-id=\"4b425c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h5><\/h5>\n<h5>Treatment in case of toxic symptoms:<\/h5>\n<p>\u2022\u00a0 Discontinuation of the anesthetic,<\/p>\n<p>\u2022\u00a0 Increased fluid intake,<\/p>\n<p>\u2022\u00a0 Administration of vasoconstrictor medications,<\/p>\n<p>\u2022\u00a0 Administration of sedatives,<\/p>\n<p>\u2022\u00a0 Application of passive oxygen therapy.<\/p>\n<p>In the event of cardiac arrest, resuscitation measures should be initiated. It's important to note that symptoms of a toxic reaction may not occur simultaneously. The use of anesthesia during a procedure requires vigilance and continuous monitoring by the practitioner.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-14\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-14-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-14-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-14-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"25\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n<div class=\"elementor-element elementor-element-4b425c7 elementor-widget elementor-widget-text-editor\" data-id=\"4b425c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h3>SECONDARY ANESTHESIA<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<p>Applied after the epidermis is disrupted, during the procedure, and typically comes in the form of a gel or liquid. It is advisable to avoid the eye area, so when pigmentation is done on this facial region, choosing a gel and applying it in small amounts is recommended. Prior to administering the agent, a consultation and assessment of the skin condition are necessary. The application procedure is as follows: it is applied for a short period (15-30-60 seconds), then rinsed off, and the pigmented area is thoroughly moisturized. If too much anesthesia is applied or it remains on the skin for too long, the treated area may become very firm, making it challenging to perform the procedure correctly. The individual response to the effect will vary.<\/p>\n<p>After administering anesthesia with adrenaline around the pigmented area, there is vasoconstriction (photo 3). In the case of lips, a side effect of using secondary anesthesia with adrenaline is skin bruising (photo 4). These symptoms usually subside within about an hour after the procedure. Many practitioners use secondary anesthesia with adrenaline at the very end of the procedure to enhance and accentuate the shading of the eyebrows for a better photo. Personally, I do not employ this trick, as I consider it an overuse of the anesthetic.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-15\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-15-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-15-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-15-1-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"26\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1.png 2160w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-300x150.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-1024x512.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-768x384.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-1536x768.png 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-2048x1024.png 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/4-1-600x300.png 600w\" sizes=\"(max-width: 600px) 100vw, 600px\" title=\"ke-martakotpakulska-fot3\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-6419-15-1-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"27\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em><strong>Photo 3<\/strong>: A white halo around the eyebrows after the application of secondary anesthesia with adrenaline.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-6419-15-2\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-15-2-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"28\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1.png\" width=\"1500\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1.png 2160w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-300x150.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-1024x512.png 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-768x384.png 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-1536x768.png 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-2048x1024.png 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/5-1-600x300.png 600w\" sizes=\"(max-width: 600px) 100vw, 600px\" title=\"ke-martakotpakulska-fot4\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-6419-15-2-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"29\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em><strong>Photo 4<\/strong>: Bruising on the upper lip after anesthesia with adrenaline, immediately after the permanent lip makeup procedure.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-16\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-16-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-16-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-16-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"30\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n<div class=\"elementor-element elementor-element-4b425c7 elementor-widget elementor-widget-text-editor\" data-id=\"4b425c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h3>SUMMARY<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<p>During the process of performing permanent makeup, the psychological aspect and technique are crucial factors. Nowadays, practitioners have access to training, advanced technology in devices, and high-quality PMU accessories. All of this largely allows for the avoidance of anesthesia, which, in my opinion, is often overused. I do not recommend beginners to start their work with anesthesia, but rather focus on proper technique and the selection of professional equipment. Skin that has been anesthetized takes longer to regenerate; for example, lip swelling can persist for up to 72 hours. It is significantly more challenging to assess the quality and intensity of color. There are clients for whom performing the procedure without anesthesia seems impossible, and in such cases, the use of a pain relief agent is justified.<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-6419-16-1-1\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"31\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-f54c0409268f-6419\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\">\n\t<a\n\thref=\"https:\/\/kwadronpmu.com\/en\/products\/\"\n\t\tclass=\"ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\" \t>\n\t\t<span>\n\t\t\t\n\t\t\tGet to know our PMU products\t\t<\/span>\n\t<\/a>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-17\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-17-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><div id=\"pg-6419-18\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-18-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-18-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-18-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"32\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"text-align: left;\">--------------------------------------------------------------------------------------------------------<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-19\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-19-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-19-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-19-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"33\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>Marta Kot-Pakulska<\/h3>\n<p>COSMETOLOGIST | PMU AND MEDICAL MICROPIGMENTATION TRAINER | LECTURER AND JUDGE<\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-6419-19-2\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-19-2-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"34\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-300x300.png\" width=\"300\" height=\"300\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-300x300.png 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-150x150.png 150w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-400x400.png 400w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-420x420.png 420w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-200x200.png 200w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51-100x100.png 100w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/Screen-Shot-2024-01-25-at-10.30.51.png 590w\" sizes=\"(max-width: 300px) 100vw, 300px\" title=\"marta-kot-pakulska\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-20\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-20-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-20-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-20-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"35\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"text-align: left;\">--------------------------------------------------------------------------------------------------------<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-21\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-21-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-21-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-21-1-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"36\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-6419\"\n\t\t\t\n\t\t>\n\n<div class=\"sow-image-container\">\n\t\t<img decoding=\"async\" src=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-300x200.jpg\" width=\"300\" height=\"200\" srcset=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-300x200.jpg 300w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-1024x683.jpg 1024w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-768x512.jpg 768w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-1536x1024.jpg 1536w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-2048x1366.jpg 2048w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-600x400.jpg 600w, https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/ke-2023_03_128-272x182.jpg 272w\" sizes=\"(max-width: 300px) 100vw, 300px\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><\/div><div id=\"pgc-6419-21-2\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-21-2-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"37\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><em>Photos. 1-4: Author's archive.<\/em><\/p>\n<p>Published with the consent and courtesy of the article's author and the editorial team of <a href=\"https:\/\/www.kosmetologiaestetyczna.com\/\">Kosmetologia Estetyczna<\/a> magazine.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-22\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-22-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-6419-22-1\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-22-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"38\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><strong>BIBLIOGRAPHY<\/strong><\/p>\n<p>1. Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy. Pain. 1979;6(3):249-252.<\/p>\n<p>2. Lee HS. Recent advances in topical anesthesia. J Dent Anesth Pain Med. 2016;16(4):237-244.<\/p>\n<p>3. K\u00fchnisch J, Daubl\u00e4nder M, Klingberg G, et al. Best clinical practice guidance for local analgesia in paediatric dentistry: an EAPD policy document. Eur Arch Paediatr Dent. 2017;18:313-321.<\/p>\n<p>4. Nawrot S, Dobrowolska S. Amazink Areola. Medical Pigmentation. Pozna\u0144: Amazink Areola; 2019:110-111.<\/p>\n<p>5. https:\/\/www.mp.pl\/bol\/wytyczne\/111006,zastosowanie-lekow-znieczuleniamiejscowego-w-leczeniu-bolu-stan-wiedzy-na-rok-2014<\/p>\n<p>6. https:\/\/www.mp.pl\/pacjent\/leki\/subst.html?id=1066<\/p>\n<p>7. Guideline on use of local anesthesia for peadiatric dental patients. American Academy of Pediatric Dentistry (AAPD). 2015;32(6):156-162.<\/p>\n<p>8. Grzanka A, Wasilewska I, \u015aliwczy\u0144ska M, Miso\u0142ek H. Nadwra\u017cliwo\u015b\u0107 na leki znieczulenia miejscowego. Anest Intens Ter. 2016;48(2):135-141.<\/p>\n<p>9. Olczak-Kowalczyk D, Szczepa\u0144ska J, Kaczmarek U. Wsp\u00f3\u0142czesna stomatologia wieku rozwojowego. Otwock: Med Tour Press International; 2017:255-259.<\/p>\n<p>10. Krasny K, Wanyura H, Mayzner-Zawadzka E, Ko\u0142acz M. Nag\u0142e przypadki w praktyce stomatologicznej: reakcja na preparaty znieczulenia miejscowego. Czas Stomat. 2005;LVIII(2):129-134.<\/p>\n<p>11. Perczak C, Wanot B, Biskupek-Wanot A. Znieczulenie miejscowe przewodowe oraz zasady post\u0119powania z chorym na bloku operacyjnym. Skrypt dla piel\u0119gniarek i student\u00f3w piel\u0119gniarstwa. Cz\u0119stochowa: Wydawnictwo Naukowe Uniwersytetu Humanistyczno-Przyrodniczego im. Jana D\u0142ugosza w Cz\u0119stochowie; 2022.<\/p>\n<p>12. Smuda A, Za\u0142\u0119ska I. Wiedza specjalist\u00f3w na temat znieczule\u0144 stosowanych w zabiegach estetycznych. Kosmetologia Estetyczna. 2018;7(5):673-581.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-23\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-23-0\"  class=\"panel-grid-cell\" ><div id=\"panel-6419-23-0-0\" class=\"so-panel widget widget_sow-button panel-first-child panel-last-child\" data-index=\"39\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-f54c0409268f-6419\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\">\n\t<a\n\thref=\"https:\/\/kwadronpmu.com\/en\/products\/\"\n\t\tclass=\"ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\" \t>\n\t\t<span>\n\t\t\t\n\t\t\tGet to know our PMU products\t\t<\/span>\n\t<\/a>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-6419-24\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-6419-24-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>MARTA KOT-PAKULSKA. Article published in Kosmetologia Estetyczna magazine (2023\/3).<\/p>\n","protected":false},"author":9,"featured_media":6356,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[74,46],"tags":[],"class_list":["post-6419","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-expert-opinion","category-pmu-guide"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.1 (Yoast SEO v27.1.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Permanent Makeup: With or Without Anesthesia? - Kwadron PMU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Permanent Makeup: With or Without Anesthesia?\" \/>\n<meta property=\"og:description\" content=\"MARTA KOT-PAKULSKA. Article published in Kosmetologia Estetyczna magazine (2023\/3).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\" \/>\n<meta property=\"og:site_name\" content=\"Kwadron PMU\" \/>\n<meta property=\"article:published_time\" content=\"2024-01-25T11:10:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-01-13T13:52:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Magdalena Szewczyk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Magdalena Szewczyk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"13 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#article\",\"isPartOf\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\"},\"author\":{\"name\":\"Magdalena Szewczyk\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/#\/schema\/person\/b3c49061754213f6529ad29fccc93020\"},\"headline\":\"Permanent Makeup: With or Without Anesthesia?\",\"datePublished\":\"2024-01-25T11:10:38+00:00\",\"dateModified\":\"2025-01-13T13:52:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\"},\"wordCount\":1944,\"publisher\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/#organization\"},\"image\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage\"},\"thumbnailUrl\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\",\"articleSection\":[\"Expert Opinion\",\"PMU Guide\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\",\"url\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\",\"name\":\"Permanent Makeup: With or Without Anesthesia? - Kwadron PMU\",\"isPartOf\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage\"},\"image\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage\"},\"thumbnailUrl\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\",\"datePublished\":\"2024-01-25T11:10:38+00:00\",\"dateModified\":\"2025-01-13T13:52:34+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage\",\"url\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\",\"contentUrl\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png\",\"width\":1080,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/kwadronpmu.com\/en\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Permanent Makeup: With or Without Anesthesia?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/#website\",\"url\":\"https:\/\/kwadronpmu.com\/en\/\",\"name\":\"Kwadron PMU\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/kwadronpmu.com\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/#organization\",\"name\":\"Kwadron PMU\",\"url\":\"https:\/\/kwadronpmu.com\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2025\/03\/logo-2.png\",\"contentUrl\":\"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2025\/03\/logo-2.png\",\"width\":150,\"height\":80,\"caption\":\"Kwadron PMU\"},\"image\":{\"@id\":\"https:\/\/kwadronpmu.com\/en\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/kwadronpmu.com\/en\/#\/schema\/person\/b3c49061754213f6529ad29fccc93020\",\"name\":\"Magdalena Szewczyk\",\"url\":\"https:\/\/kwadronpmu.com\/en\/author\/magdasz\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Permanent Makeup: With or Without Anesthesia? - Kwadron PMU","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia","og_locale":"en_US","og_type":"article","og_title":"Permanent Makeup: With or Without Anesthesia?","og_description":"MARTA KOT-PAKULSKA. Article published in Kosmetologia Estetyczna magazine (2023\/3).","og_url":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia","og_site_name":"Kwadron PMU","article_published_time":"2024-01-25T11:10:38+00:00","article_modified_time":"2025-01-13T13:52:34+00:00","og_image":[{"width":1080,"height":1080,"url":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png","type":"image\/png"}],"author":"Magdalena Szewczyk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Magdalena Szewczyk","Est. reading time":"13 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#article","isPartOf":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia"},"author":{"name":"Magdalena Szewczyk","@id":"https:\/\/kwadronpmu.com\/en\/#\/schema\/person\/b3c49061754213f6529ad29fccc93020"},"headline":"Permanent Makeup: With or Without Anesthesia?","datePublished":"2024-01-25T11:10:38+00:00","dateModified":"2025-01-13T13:52:34+00:00","mainEntityOfPage":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia"},"wordCount":1944,"publisher":{"@id":"https:\/\/kwadronpmu.com\/en\/#organization"},"image":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage"},"thumbnailUrl":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png","articleSection":["Expert Opinion","PMU Guide"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia","url":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia","name":"Permanent Makeup: With or Without Anesthesia? - Kwadron PMU","isPartOf":{"@id":"https:\/\/kwadronpmu.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage"},"image":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage"},"thumbnailUrl":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png","datePublished":"2024-01-25T11:10:38+00:00","dateModified":"2025-01-13T13:52:34+00:00","breadcrumb":{"@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#primaryimage","url":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png","contentUrl":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2024\/01\/2.png","width":1080,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/kwadronpmu.com\/en\/permanent-makeup-with-or-without-anesthesia#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/kwadronpmu.com\/en"},{"@type":"ListItem","position":2,"name":"Permanent Makeup: With or Without Anesthesia?"}]},{"@type":"WebSite","@id":"https:\/\/kwadronpmu.com\/en\/#website","url":"https:\/\/kwadronpmu.com\/en\/","name":"Kwadron PMU","description":"","publisher":{"@id":"https:\/\/kwadronpmu.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/kwadronpmu.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/kwadronpmu.com\/en\/#organization","name":"Kwadron PMU","url":"https:\/\/kwadronpmu.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/kwadronpmu.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2025\/03\/logo-2.png","contentUrl":"https:\/\/kwadronpmu.com\/wp-content\/uploads\/2025\/03\/logo-2.png","width":150,"height":80,"caption":"Kwadron PMU"},"image":{"@id":"https:\/\/kwadronpmu.com\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/kwadronpmu.com\/en\/#\/schema\/person\/b3c49061754213f6529ad29fccc93020","name":"Magdalena Szewczyk","url":"https:\/\/kwadronpmu.com\/en\/author\/magdasz"}]}},"_links":{"self":[{"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/posts\/6419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/comments?post=6419"}],"version-history":[{"count":0,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/posts\/6419\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/media\/6356"}],"wp:attachment":[{"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/media?parent=6419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/categories?post=6419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kwadronpmu.com\/en\/wp-json\/wp\/v2\/tags?post=6419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}